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What are some examples of negative feedback loops?

An example of a negative feedback loop is the regulation of blood pressure (Figure 1). An increase in blood pressure is detected by receptors in the blood vessels that sense the resistance of blood flow against the vessel walls. The receptors relay a message to the brain, which in turn sends a message to the effectors, the heart and blood vessels.

What is involved in a negative feedback loop?

A negative feedback loop occurs in biology when the product of a reaction leads to a decrease in that reaction. In this way, a negative feedback loop brings a system closer to a target of stability or homeostasis. Negative feedback loops are responsible for the stabilization of a system, and ensure the maintenance of a steady, stable state.

How does a negative feedback loop help maintain homeostasis?

One well-known negative feedback loop that maintains homeostasis is associated with thermoregulation. When an organism is physically active, the metabolic processes necessary to move result in a higher body temperature. In humans this temperature is detected by receptors in the brain and skin.


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