Kras.nl - KRAS - Wikipedia

Provided by Alexa ranking, kras.nl has ranked N/A in N/A and 963,662 on the world. kras.nl reaches roughly 3,251 users per day and delivers about 97,534 users each month. The domain kras.nl uses a Commercial suffix and it's server(s) are located in N/A with the IP number 195.128.186.60 and it is a .nl domain.

WebKRAS (Kirsten rat sarcoma virus) is a gene that provides instructions for making a protein called K-Ras, a part of the RAS/MAPK pathway. The protein relays signals from outside the cell to the cell's nucleus.

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KRAS - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/KRAS

WebKRAS (Kirsten rat sarcoma virus) is a gene that provides instructions for making a protein called K-Ras, a part of the RAS/MAPK pathway. The protein relays signals from outside the cell to the cell's nucleus.

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KRAS mutation: from undruggable to druggable in cancer
nature.com

https://www.nature.com/articles/s41392-021-00780-4

WebNov 15, 2021 · Kirsten rat sarcoma viral oncogene homologue (KRAS) is the best-known oncogene with the highest mutation rate among all cancers and is associated with a series of highly fatal cancers, including...

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KRAS gene: MedlinePlus Genetics
medlineplus.gov

https://medlineplus.gov/genetics/gene/kras/

WebThe KRAS gene provides instructions for making a protein called K-Ras that is part of a signaling pathway known as the RAS/MAPK pathway. Learn about this gene and related health conditions.

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Targeting KRAS in cancer | Nature Medicine
nature.com

https://www.nature.com/articles/s41591-024-02903-0

WebApr 18, 2024 · Oncogenic KRAS is a central regulator of immunity and has long been known to promote an immunosuppressive signaling network in the cancer microenvironment through tumor cell expression of ...

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The current understanding of KRAS protein structure and dynamics
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965201/

WebDec 26, 2019 · GTPase KRas (KRAS) is a signal transducer protein, which plays an important role in various cellular signalling events such as in regulation of cell proliferation. It is a critical hub in the cell circuitry, as upon an upstream stimulus it transduces activating signals to several cellular signalling pathways, including the mitogen-activated ...

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Targeting the KRAS mutation for more effective cancer treatment
mdanderson.org

https://www.mdanderson.org/cancerwise/targeting-the-kras-mutation-for-more-effective-cancer-treatment.h00-159458478.html

WebFeb 12, 2021 · KRAS mutations are present in approximately 25% of tumors, making them one of the most common gene mutations linked to cancer. They are frequent drivers in lung, colorectal and pancreatic cancers. KRAS drives 32% of lung cancers, 40% of colorectal cancers, and 85% to 90% of pancreatic cancer cases.

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KRAS Gene - GeneCards | RASK Protein | RASK Antibody
genecards.org

https://www.genecards.org/cgi-bin/carddisp.pl?gene=KRAS

WebApr 3, 2024 · KRAS (KRAS Proto-Oncogene, GTPase) is a Protein Coding gene. Diseases associated with KRAS include Schimmelpenning-Feuerstein-Mims Syndrome and Oculoectodermal Syndrome. Among its related pathways are Prolactin Signaling and Downstream signaling of activated FGFR2.

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The origins and genetic interactions of KRAS mutations are ... - Nature
nature.com

https://www.nature.com/articles/s41467-021-22125-z

WebMar 22, 2021 · 80 Citations. 76 Altmetric. Metrics. Mutational activation of KRAS promotes the initiation and progression of cancers, especially in the colorectum, pancreas, lung, and blood plasma, with varying...

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Oncogenic KRAS: Signaling and Drug Resistance - PMC
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616169/

WebNov 9, 2021 · KRAS is one of the oncogenic proteins and best well-known GTPase proteins. Although KRAS serves as regulation of cellular process, abnormal mutated and GTP-bound KRAS is highly expressed in human cancers. Understanding biological characteristics and precise signaling of KRAS proteins is essential for targeted cancer therapy.

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What’s new in KRAS mutation research? - MD Anderson Cancer …
mdanderson.org

https://www.mdanderson.org/cancerwise/what-s-new-in-kras-mutation-research-.h00-159696756.html

WebApril 04, 2024. What’s new in KRAS mutation research? BY Christina Sumners. Cancer cells often develop genetic mutations that initiate and sustain the growth of tumors. The most frequently mutated of these oncogenic driver genes, called KRAS, is associated with some of the most fatal cancer types: lung, pancreatic and colorectal cancers.

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963,662

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kras.nl	NS	IN	300	Target: ns2.tui.nl

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