T Cell Activation - PMC - National Center for Biotechnology …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740335/
WebUpon T cell activation, IκB is phosphorylated by the IκB kinase (IKK) complex, ubiquitinylated, and degraded, allowing NFκB to translocate into the nucleus, where it actives genes involved in the function, survival, and homeostasis of T cells (reviewed in 74). While the general pathway of NFκB activation has been known for some time, the ...
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