pegylated | PEGylation

Keyword	CPC	PCC	Volume	Score	Length of keyword
pegylated	0.05	0.2	7520	69	9

Keyword	CPC	PCC	Volume	Score
pegylated	1.47	0.1	4249	31
pegylated interferon	0.15	0.9	1687	34
pegylated liposomal doxorubicin	0.33	0.4	463	73
pegylated lipid	1.63	0.6	8869	54
pegylated g-csf	0.68	0.8	3474	25
pegylated interferon alpha	1.62	0.8	3521	84
pegylated asparaginase	0.68	0.7	125	86
pegylated meaning	1.85	0.8	4971	52
pegylated drugs	0.41	0.3	1498	42
pegylated protein	1.73	0.4	3775	64
pegylated doxorubicin	1.24	1	8826	45
pegylated liposomes	0.29	0.6	6517	97
pegylated filgrastim	0.52	0.9	6957	8
pegylated interferon alfa	1.14	0.4	3222	49
pegylated peptide	1.41	0.3	2469	25
pegylated nanoparticles	0.09	0.3	6270	61
pegylated interferon alfa-2a	0.61	0.2	7402	10
pegylated interferon lambda	0.22	0.8	3407	78

Search Results related to pegylated on Search Engine

PEGylation - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/PEGylation

WEBPEGylation (or pegylation) is the process of both covalent and non-covalent attachment or amalgamation of polyethylene glycol (PEG, in pharmacy called macrogol) polymer chains to molecules and macrostructures, such as a drug, therapeutic protein or vesicle, which is then described as PEGylated.

DA: 47 PA: 100 MOZ Rank: 10

PEGylation - an overview | ScienceDirect Topics
sciencedirect.com

https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pegylation

WEBPEGylation is a chemical modification that involves conjugation of active polyethylene glycol (PEG) to a therapeutic protein/peptide or to a delivery system (nanoparticle). PEGylation offers several advantages such as favorable pharmacokinetics, more stability, and enhanced therapeutic activity [1].

DA: 55 PA: 2 MOZ Rank: 13

What is PEGylation and why is it an Important Process?
enzolifesciences.com

https://www.enzolifesciences.com/science-center/technotes/2020/november/what-is-pegylation-and-why-is-it-an-important-process?/

WEBPEGylation is used as a strategy to overcome challenges such as instability, inadequate circulation half-life and immunogenicity of a drug candidate intended for a therapeutic use. Figure 1: Structure of Single PEG chain. Figure 2: Mechanism for synthesis of mPEG by anionic polymerization.

DA: 89 PA: 51 MOZ Rank: 15

Effect of pegylation on pharmaceuticals | Nature Reviews Drug …
nature.com

https://www.nature.com/articles/nrd1033

WEBPegylation is an alternative method that overcomes these deficiencies 8, 9 by attaching polyethylene glycol (PEG) chains to polypeptides or other candidate molecules. In fact, liposomes are now...

DA: 63 PA: 44 MOZ Rank: 25

Pegylation Definition & Meaning | Merriam-Webster Medical
merriam-webster.com

https://www.merriam-webster.com/medical/pegylation

WEBThe meaning of PEGYLATION is the attachment of polyethylene glycol chains to a molecule. How to use pegylation in a sentence.

DA: 10 PA: 39 MOZ Rank: 95

Protein PEGylation for cancer therapy: bench to bedside - PMC
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732144/

WEBNov 29, 2018 · Several PEGylated drugs are being used for diseases like anemia, kidney disease, multiple sclerosis, hemophilia and cancers. With the advancement and increased specificity of the PEGylation process, the world of drug therapy, and specifically cancer therapy could benefit by utilizing this technique to create more stable and non …

DA: 39 PA: 62 MOZ Rank: 69

PEGylated therapeutics in the clinic - PMC - National Center for
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10771556/

WEBSep 22, 2023 · Here, we summarize the diverse types of PEGylation strategies, the key advantages of PEGylated therapeutics over their parent drugs, and the broad applications and impacts of PEGylation in clinical settings.

DA: 59 PA: 15 MOZ Rank: 63

PEGylation of Biopharmaceuticals: A Review of Chemistry
sciencedirect.com

https://www.sciencedirect.com/science/article/pii/S0022354915001306

WEBFeb 1, 2016 · This review describes the properties of PEG itself, the history and evolution of PEGylation chemistry, and provides examples of PEGylated drugs with an established medical history. A trend toward the use of complex PEG architectures and larger PEG polymers, but with very pure and well-characterized PEG reagents is described.

DA: 71 PA: 100 MOZ Rank: 66

The impact of PEGylation on biological therapies - PubMed
nih.gov

https://pubmed.ncbi.nlm.nih.gov/18778113/

WEBThe term PEGylation describes the modification of biological molecules by covalent conjugation with polyethylene glycol (PEG), a non-toxic, non-immunogenic polymer, and is used as a strategy to overcome disadvantages associated with some biopharmaceuticals. PEGylation changes the physical and chemical properties of the biomedical molecule, …

DA: 87 PA: 86 MOZ Rank: 68

Moving Protein PEGylation from an Art to a Data Science
acs.org

https://pubs.acs.org/doi/10.1021/acs.bioconjchem.2c00262

WEBAbstract. PEGylation is a well-established and clinically proven half-life extension strategy for protein delivery. Protein modification with amine-reactive poly (ethylene glycol) (PEG) generates heterogeneous and complex bioconjugate mixtures, often composed of several PEG positional isomers with varied therapeutic efficacy.

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