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What is Guillain-Barré syndrome (GBS)?

Guillain-Barré syndrome (GBS) is a rare neurological disorder in which the body's immune system mistakenly attacks part of its peripheral nervous system—the network of nerves located outside of the brain and spinal cord. GBS can range from a very mild case with brief weakness to nearly devastating paralysis,...

Can dogs get Guillain-Barré syndrome?

Two dogs subsequently developed a chronic progressive course and two had a relapsing, corticosteroid-responsive course. Acute canine idiopathic polyneuropathy (ACIP) shares many features with the Guillain-Barré syndrome, and may be a naturally occurring model of the human disorder.

How does GBS affect the nervous system?

In some forms of GBS, antibodies made by the person to fight a Campylobacter jejuni bacterial infection attack axons in the motor nerves. This causes acute motor axonal neuropathy, which is a variant of GBS that includes acute paralysis and a loss of reflexes without sensory loss.

What causes acute motor axonal neuropathy in GBS?

This causes acute motor axonal neuropathy, which is a variant of GBS that includes acute paralysis and a loss of reflexes without sensory loss. Campylobacter infections can be caused by ingesting contaminated food or from other exposures. The infected person’s body then makes antibodies against Campylobacter.


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