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syndrome (GBS) consists of a group of neuro-pathic conditions characterized by progressive weakness and diminished or absent reflexes.1,2 Although GBS is uncommon, early diagnosis by family physicians and prompt referral for aggressive therapy may significantly improve outcomes.What causes Guillain-Barre syndrome (GBS)?
The exact cause of Guillain-Barre syndrome is unknown. But two-thirds of patients report symptoms of an infection in the six weeks preceding. These include respiratory or a gastrointestinal infection or Zika virus.How does GBS affect the nervous system?
In some forms of GBS, antibodies made by the person to fight a Campylobacter jejuni bacterial infection attack axons in the motor nerves. This causes acute motor axonal neuropathy, which is a variant of GBS that includes acute paralysis and a loss of reflexes without sensory loss.What is the prognosis of Guillain-Barré syndrome (GBS)?
Some individuals still report ongoing improvement after 2 years. About 30 percent of those with Guillain-Barré have residual weakness after 3 years. About 3 percent may suffer a relapse of muscle weakness and tingling sensations many years after the initial attack.