Glucagon-like peptide 1-based therapies for the treatment of ... - UpToDate
https://www.uptodate.com/contents/glucagon-like-peptide-1-based-therapies-for-the-treatment-of-type-2-diabetes-mellitus
WEBFeb 5, 2024 · It binds to a specific GLP-1 receptor, which is expressed in various tissues, including pancreatic beta cells, pancreatic ducts, gastric mucosa, kidney, lung, heart, skin, immune cells, and the hypothalamus [ 4,6 ]. GLP-1 exerts its main effect by stimulating glucose-dependent insulin release from the pancreatic islets [ 4 ].
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