Use of a Modified Preexposure Prophylaxis
https://www.cdc.gov/mmwr/volumes/71/wr/mm7118a2.htm
OverviewBackgroundReasons for Revisions of RecommendationsRedefined Risk CategoriesMinimum Acceptable Rabies Antibody Titer LevelEvidence for Updated Vaccine Schedule and Recommendations for Booster Doses and Titer ChecksRecommendationsClinical GuidanceImplications of These UpdatesFuture ResearchThe Work Group identified additional considerations that are essential to effective administratio…Coadministration of IM rabies PrEP and chloroquine or drugs related to chloroquine. Recent data show that although concomitant administration of chloroquine and IM rabies PrEP is associated with a significant reduction in rabies antibody titer, the reduced levels remain >0.5 IU/mL (14). T… The Work Group identified additional considerations that are essential to effective administratio…Coadministration of IM rabies PrEP and chloroquine or drugs related to chloroquine. Recent data show that although concomitant administration of chloroquine and IM rabies PrEP is associated with a significant reduction in rabies antibody titer, the reduced levels remain >0.5 IU/mL (14). T… Approach to PrEP in special populations, including persons suspected or confirmed to be immu…However, among persons with primary or secondary immunodeficiencies, the immune response to vaccines, including rabies vaccines, can be suboptimal. ACIP recommends that, when possible, vaccination be delayed until a temporary immunocompromising condition has resolved or immu…
The Work Group identified additional considerations that are essential to effective administratio…Coadministration of IM rabies PrEP and chloroquine or drugs related to chloroquine. Recent data show that although concomitant administration of chloroquine and IM rabies PrEP is associated with a significant reduction in rabies antibody titer, the reduced levels remain >0.5 IU/mL (14). T…
Approach to PrEP in special populations, including persons suspected or confirmed to be immu…However, among persons with primary or secondary immunodeficiencies, the immune response to vaccines, including rabies vaccines, can be suboptimal. ACIP recommends that, when possible, vaccination be delayed until a temporary immunocompromising condition has resolved or immu…
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